In the experiment above, wild type (WT, white bar) or double knockout mice (DKO,
ID: 148036 • Letter: I
Question
In the experiment above, wild type (WT, white bar) or double knockout mice (DKO, black bar) were given a supply of food pellets that they could eat any time they would like. Blood samples were taken and glucose in the blood was measured.
What is the experiment measuring?
D. The rate of glucose uptake
What can you conclude from this data?
C. DKO mice absorb more glucose than WT
The blood concentration is given in mg/dL. Calculate the approximate concentrations of blood glucose in mM. The molecular weight of glucose is 180 g/mol. There are 10 dL in 1 L.
D. [Blood glucose] is approximately 14 mM in WT mice and 2.2 mM in DKO mice.
The transport of glucose out of intestinal cells and into the blood is passive. Predict whether the intracellular concentration of glucose [glucose]i of the intestinal cells will be higher or lower than in the blood.
A. The transport of glucose into the intestinal epithelial cells 0 050505 32211 (1pfou) asoonl6 poolaExplanation / Answer
1. C , the concentration of blood glucose.
As we can see in the graph, y axis represents the concentration of blood glucose in mg/dl.
2. B- DKO mice absorbs less glucose than WT, as we can see in graph blood glucose concentration in WT is 255mg/dl while in DKO it is 40 mg/dl. Glucose is absorbed across the intestinal wall to the bloodstream.
3. D- blood glucose concentration is approximately 14mM in WT mice and 2.2 mM in DKO mice.
When the concentration is in mg/dl and has to be converted to mM/l, it should be divided by 18 or multiplied by 0.055. You will get the answer in mM/L.
255*0.055= 14.025mM/l
40* 0.055= 2.2 mM/l
4. B. Concentration of glucose of the intestinal cells will be higher than blood
actually the transport of glucose is done by both facilitated diffusion or by active transport. Facilitated diffusion is done by passive transport , transport will be along the concentration gradient. But if transport is done by active transport , it will be against the concentration gradient.