Describe leading strand and lagging strand DNA replication using the following t
ID: 164355 • Letter: D
Question
Describe leading strand and lagging strand DNA replication using the following terms in your description: helicase, primase, RNA primer, DNA polymerase I, DNA polymerase III, DNA ligase, Okazaki fragments, leading strand and lagging strand. Describe leading strand and lagging strand DNA replication using the following terms in your description: helicase, primase, RNA primer, DNA polymerase I, DNA polymerase III, DNA ligase, Okazaki fragments, leading strand and lagging strand. Describe leading strand and lagging strand DNA replication using the following terms in your description: helicase, primase, RNA primer, DNA polymerase I, DNA polymerase III, DNA ligase, Okazaki fragments, leading strand and lagging strand.Explanation / Answer
LEADING STRAND :When replication begins, the two parent DNA strands are separated. One of these is called the leading strand.it replicates continuously.
LAGGING STRAND:A lagging strand is one of two strands of DNA found at the replication fork, or junction, in the double helix,A lagging strand requires a slight delay before undergoing replication, and it must undergo replication discontinuously in small fragments.
leading strand and lagging strand DNA replication:
DNA replication to work in a continuous fashion. But this only occurs on the leading strand.DNA helicase is useful for moving down the line, opening the replication fork more and more. So, the two enzymes work in sync with each other. The more DNA helicase splits open the fork, the more DNA polymerase keeps adding on daughter nucleotides.A primase can be used to initiate DNA synthesis at known sequences in a template DNA molecule.An RNA Primer Synthesized by Primase Enables DNA Synthesis lagging-strand template and initiates synthesis of another RNA primer.only a single RNA primer is required. DNA polymerase I builds the daughter strand by matching new strands ,it is used in the synthesis of the leading strand .deal with such a mismatched primer it is used for removal of RNA primers.DNA polymerase III go of the lagging-strand template after adding about 1000 nucleotides.There are two molecules ofDNA polymerase III at a replication fork. DNA ligase is used to complete replication in the lagging strand of DNA. DNA ligase is required for joining Okazaki fragments.Okazaki fragmentsare made by DNA polymerase working for short distances in the 3' to 5' direction. The fragments are bound together by the enzyme DNA ligase in order to complete replication in the lagging strand of DNA.Okazaki fragments are short, newly synthesized DNAfragments that are formed on the lagging template strand during DNA replication.