An enzyme with a high Km Value(Michaelis-Menten) A)Is weak at binding substrate
ID: 181904 • Letter: A
Question
An enzyme with a high Km Value(Michaelis-Menten) A)Is weak at binding substrate B)Is less efficient at catalysis than an enzyme with lower Km C) Can be more efficient at catalysis than an enzyme with a higher Km D) Cannot be more efficient at catalysis than an enzyme with a higher Km An enzyme with a high Km Value(Michaelis-Menten) A)Is weak at binding substrate B)Is less efficient at catalysis than an enzyme with lower Km C) Can be more efficient at catalysis than an enzyme with a higher Km D) Cannot be more efficient at catalysis than an enzyme with a higher Km A)Is weak at binding substrate B)Is less efficient at catalysis than an enzyme with lower Km C) Can be more efficient at catalysis than an enzyme with a higher Km D) Cannot be more efficient at catalysis than an enzyme with a higher KmExplanation / Answer
Answer
A) Is weak at binding substrate
Km is the Michaelis-Menten constant that shows the concentration of the substrat at which the reaction velocity is equal to one half of the maximal velocity for the reaction.
It is a measure of how well a substrate binds with a given enzyme, also known as its binding affinity. An equation with a low Km value indicates a high binding affinity, as the reaction will achieve Vmax more rapidly.
An enzyme that acts on a substrate present at a low concentration has a lower Km than an enzyme that acts on a substrate that is in higher concentration.
A high Km indicates that the enzyme does not bind efficiently with the substrate, and Vmax will be reached at higher substrate concentration.
A small Km indicates high affinity for substrate, therefore, Vmax will be reached more quickly at low substrate concentration