Describe how you can determine which type of macromolecule you have. (I0 pts 13.
ID: 189906 • Letter: D
Question
Describe how you can determine which type of macromolecule you have. (I0 pts 13. A transmembrane protein has 1000 amino acids. The seventh amino acid is found in between the tails of the cell membrane. Amino acid 36 is found on the outer surface of the protein and it interacts with the aqueous environment but would not form ionic bonds with other charged molecules. Amino acids 518 and 823 are covalently bonded to each other and contribute to the stabilization of the protein conformation. A weak hydrogen bond forms between amino acids 888 and 989 and they are found on the external surface of the protein. Identify each of the numbered amino acids by structural group and name. (NOTE: For this question, no two answers should be the same. For most positions, there are more than one specific amino acid that would be correct. Again, the probability that two students would come up with the exact same answer is EXTREMELY small.) (18 pt total; 3 pts/amino acid) Backspace up End Pae Down T ShiftExplanation / Answer
7 th position amino acid must be hydrophobic in nature, as it is in between the tail of cell membrane. Therefore, they can be glycine, proline, valine, leucine, isoleucine, methionine, phenylalanine, and tryptophan
36th position amino acid must be hydrophilic in nature as they interact with the aquous environment, therefore, chances could be serine, threonine, glutamine, cysteine and asparagine, tyrosine
NOTE: lysine, histidine, arginine aspartate and glutamate are also hydrophilic amino acid but they participate in an ionic bond formation that's why they cannot be at 36th position as per your premise.
both 518th and 823rd amino acid are lysine as it has ability to make s-s covalent bond and also provide stability to protein.
888th and 989th amino acid makes weak hydrogen bond which bring us to consider tyrosin, tryptophan and phenylalanine as they make weak hydorgen bond but as these two positional amino acid are on the surface which means tryptophan and phenyl alanine have very less chances to be at the surface due to their hydrophobic nature, therefore, we can conclude that both 888th and 989th amino acid is tyrosin and it also a hydrophilic.