See Hint A research lab is using DNA microarrays to examine gene expression in S
ID: 192443 • Letter: S
Question
See Hint A research lab is using DNA microarrays to examine gene expression in Salmonella enterica during stress. It was not tations, 20 new genes were expressed (as compared to normal laboratory growth conditions): when exposed to e expressed; and when exposed to low pH, 15 new genes were expressed. The lab then subjected the ed that when stress, 24 new genes wer bacteria to growth in macrophage phagolysosomes, which mimicked the previous three conditions, and noted 59 new genes being expressed. Which of the following would best explain this result? Choose one: O A. The experiment is probably wrong and should be repeated since the number should be lower than 59 because it is likely that some of the stress-induced genes would overlap, so the total number would be lower than adding up the results for the three individual changes in gene expression. the DNA microarrays due to the low pH conditions. some genes wouldn't be expressed under the combined conditions, and some new genes would likely be o B. The results are probably wrong, and the experiment should be repeated since there should be less binding on OC. The result is most likely a coincidence since some of the genes for the different stressors would overlap expressed due to the unrecognized stress of growing in the phagolysosome. OD. The results are probably wrong, and the experiment should be repeated since there would likely be even more stress-induced gene expression due to not only the three stressors that were encountered individually but also due to any additional stress not yet accounted for due to being in the phagolysosome 0 E. This is expected since all three stresses are encountered and the effect would be additive, so the 59 genes would be the same as the 20 genes for low-nutrient stress, the 24 genes for oxidative stress, and the 15 genes for low pH stress 8 OF 13 QUESTIONS COMPLETEDExplanation / Answer
the correct option according to me would be the last one.
the result is correce and expected since all the stress conditions are different and a cell might contain or express different genes to counter different stress types.