Individuals with Klinefelter syndrome have an XXY set of sex chromosomes. Which
ID: 199140 • Letter: I
Question
Individuals with Klinefelter syndrome have an XXY set of sex chromosomes. Which of these describes a way this abnormality can arise? Select all that apply.
Nondisjunction during Meiosis I in the father results in an XY sperm, which fertilizes an X egg
Nondisjunction during Meiosis II in the mother results in an XX egg, which is fertilized by a Y sperm from the father
Nondisjunction during Meiosis I in the mother results in an XX egg, which is fertilized by a Y sperm from the father
Nondisjunction during Meiosis II in the father results in an XY sperm, which fertilizes an X egg
Explanation / Answer
All of the answer are correct
Note- nondysjunction can arise during meiosis 1 or 2 during gamete formation, which cause failure of chromosome to move apart during cell division and causing two chromosome to move together toward one pole during division.