Case study help!!!! 44 year old female with high blood pressure issues, but mana
ID: 207915 • Letter: C
Question
Case study help!!!!
44 year old female with high blood pressure issues, but managed with medications.Patient complains of flu-like symptoms.she said onset of symptoms started during her trip to Farmington, New Mexico. She returned yesterday. Patient also complains of pain and swelling on leg.
Quick check with PDR and resident…..reveals swollen lesion is more than likely a bubo caused as a result of bubonic plague!The Resident states that immediate meds are needed and you wonder…the black death in New Mexico? How does this happen?
Resident states, its all about gene expression? What?
Below is the Case Study Form:
Patient History:
Patient #:_______________________
Age:___________________________
Sex:___________________________
Occupation:______________________
Family History/Preconditions:
Relevant Recent History:
Signs and Symptoms:
Signs:
Symptoms:
Microbiology:
Causative Organism(s):_________________
Modes of Transmission:_________________
____________________________________
Prevention:___________________________
Virulence Factor:
Mechanism of Virulence Factor:
Treatment:
Drug Name:__________________________
Class of Drug:________________________
____________________________________
Type of Admission:____________________
Potential Side Effects of Drug Treatment:
Mechanism of Treatment:
Lab Work:
Type of Sample Received:_______________
____________________________________
Test(s) To Determine Causative Organism:
Positive Results of Test(s):
Explanation / Answer
Patient #: 01
Age: 44
Sex: Female
Occupation: Unknown
Family History/Preconditions: None
Relevant Recent History: Recently visited Farmington, New Mexico.
Signs and Symptoms:
Signs: Bubonic plague
Symptoms: Pain, swelling in the leg, flu-like symptoms (Fatigue, fever)
Microbiology: Bacterial agent
Causative Organism(s): Yersinia pestis
Modes of Transmission: Contact with infected tissue, flea bite, cough of an infected person.
Prevention: avoid contact with infected person, insect repellent.
Virulence Factor: Factor 1, V-Antigen, Plasminogen Activator, Yersiniabactin, Yop effectors
Mechanism of Virulence Factor: invasion in host tissue, scavenge nutrient, evade immune system, anti-phagocytosis
Treatment:
Drug Name: Streptomycin
Class of Drug: aminoglycoside antibiotics
Type of Admission: Intramuscular administration
Potential Side Effects of Drug Treatment: Hypotension, headache, nausea, skin rash, anemia, weakness
Mechanism of Treatment: Blocks 30S ribosomal subunits.
Lab Work:
Type of Sample Received: blood, parts of swollen lymph node
Test(s) To Determine Causative Organism: Blood cultured with BACTEC Media and SEPTI-CHEK BHI, then on TSA w/5% Sheep Blood/MacConkey II Agar.
Positive Results of Test(s): Gray-white, translucent colonies. and non-lactose fermentor. Should test positive for catalase.