Imagine that you have engineered a set of genes, each encoding a protein with a
ID: 218135 • Letter: I
Question
Imagine that you have engineered a set of genes, each encoding a protein with a pair of conflicting signal sequences that specify different cellular compartments. If the genes were expressed in a cell, predict where the proteins produced from these genes would accumulate. Explain your reasoning.1) signals for import into the ER and import into lysosomes
Imagine that you have engineered a set of genes, each encoding a protein with a pair of conflicting signal sequences that specify different cellular compartments. If the genes were expressed in a cell, predict where the proteins produced from these genes would accumulate. Explain your reasoning.
1) signals for import into the ER and import into lysosomes
Imagine that you have engineered a set of genes, each encoding a protein with a pair of conflicting signal sequences that specify different cellular compartments. If the genes were expressed in a cell, predict where the proteins produced from these genes would accumulate. Explain your reasoning.
1) signals for import into the ER and import into lysosomes
Explanation / Answer
Signal for import into the ER
As the proteins are synthesized in the ribosomes attached to the ER. So when, there is a presence of conflicting sequence, the proteins would enter the extracellular spaces while going into the Golgi apparatus.
Signal for import into the lysosomes
As the proteins are transported in the from the ER into Golgi apparatus and to lysosomes for packaging. So if signal for import into lysosome is missing, then the proteins will go till Golgi apparatus . They will not go to the lysosome.