How is number 5 the correct answer? Example Question for Mutation analysis of pr
ID: 219078 • Letter: H
Question
How is number 5 the correct answer?
Example Question for Mutation analysis of protein transport among organelles: You identified a novel organism that transports proteins through 4 different organelles, Organelle I, II, III, and IV. To identify an order of protein transport among the ofganelles, you isolated mutants of the organisms; Class 1, Class 2, Class 3, and Cass 4. Class 1, Class 2, Class 3, and Cass 4 mutants accumulate the proteins in organelle I, II, III, IV, respectively. The proteins accumulate in different organelles when double mutants were analyzed. The results show below. Proteins accumulated Organelle II Organelle I Organelle IV Organelle II Organelle IV Organelle IV 2 Double mutants Class 1 and 2 Class 1 and 3 Class 1 and 4 Class 2 and 3 Class 2 and 4 Class 3 and 4 3 2 4 ? What is the order of protcin transport in the organism? 3 H 1· 1?11 ? 111 ? IVExplanation / Answer
From the given data we understand that
Thus, Class 1,2,3,4 mutations occur after Organelle IV, thus it present at the starting of the chain.
No mutation occurs after Organelle III, thus it occurs at the end of the chain
Three types of mutations( Classes 1,2 and 3) occur after Organelle II whereas only 2 types of mutations (Classes 1 and 3) occur after Organelle I, thus we can understand that Organelle II occurs before Organelle I.
Thus from the above analysis, we can understand that option (5) is correct.