Answer questions 9-10 by referring to the figure below. The figure shows the exp

Question

Answer questions 9-10 by referring to the figure below. The figure shows the expression of several transcription factors in the developing Drosophila embryo. The Bicoid (Bcd, green) and Hunchback (Hb, black) proteins are activators; the Sloppy-paired (Slp1, dark blue), Giant (Gt, yellow), and Krüppel (Kr, red) proteins are repressors The location of even-skipped stripe #2 expression is indicated in light blue. 9. Which of the following mutations could cause an expansion of even-skipped expression towards the anterior of the embryo? Embryo length a) bicoid loss-of-function b) Krüppel loss-of-function c) Krüppel gain-of-function d) Giant loss-of-function 10. Which of the following mutations could cause an expansion of even-skipped expression towards the posterior of the embryo? Anterior Posterior a) bicoid loss-of-function b) Krüppel loss-of-function c) Krüppel gain-of-function d) Giant loss-of-function

Explanation / Answer

Question 9 - The second option (b) is the correct answer. Even skipped (eve) genes regulate by two proteins Kruppel and Giant. Kruppel negatively regulate the eve gene in anterior region. Therefore, its loss of function would cause the gain of eve genes in anterior region.

Question 10- the fourth option (d) is the correct answer. The giant gene regulates eve genes posteriorly.

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