Could you please answer these questions? I have tried to answer them but I am no
ID: 271404 • Letter: C
Question
Could you please answer these questions? I have tried to answer them but I am not sure if I am right or not.
New Tab X Student Home (24) Awalem Kh Student Home B Take Test Assigr X © QUESTION 1 HX 1) The Sodium, In patients with × + ?? https://cas.ecampuswvu.edu/webapps/assessment/takenaunch.js 60% ? Search QUESTION1 The main roic of tho proten hemogicbn is to transpart cxyaen. Rod blood celsusc hemoglotin to pick up oxyecn trom he lungs and then crap it cft at subaoquert cela. Red blood cclla aiso carry suga iglucose, around body Giu0000 pid0d up n t ? stormach and droppoa ar subcoquant cela won an IraMdual has sickle ool anomía bood doea n0K taw properly and angen and gugar are not The rs4questions are xave ger buns: Yeu shoud be able to ind the ancwer in your notes or ycur texcbock Hamcglobin is a proten. Duing protein syntiesis (and al macromolocie synmeais) ATPlanargy is spent to fom which covaone bond? Bond botwoon reononer andcamer OBond borwoon camar and assontkr QUESTION 2 s valine. Which is more hydrophobio, gutemic acid or valine? They aie both hydophobic ari10xib The denge tom ?uari aad to walne decreases meractions wi THIN the prterand ncreases nterstons BETAE EN hemog obn molecules (see the mage below T is cuses long chan Normal (Wild-Type) Haemoglobin 0 Type here to search 6:29 PM 5/18/2018 2 ^ ENGExplanation / Answer
1. During protein synthesis at least four energy units (ATP and GTP) are required for each peptide bond formation.
First ATP is spent during activation of amino acid. In this process amino acid is coupled to its specific tRNA leads to the formation of aminoacyl-tRNAs and it requires hydrolysis of ATP.
Second GTP is used in initial binding of amino acid at the initiator site on mRNA-30S unit. GTP hydrolysis by initiation factor-2 (IF-2) releases all initiation factors from the complex.
Third GTP is hydrolyzed during elongation step; GTP is bound to elongation factor EF-TU. Incoming aminoacyl-tRNA binds to GTP-EF-TU and after position at correct position on (A site) initiation complex GTP gets hydrolyzed and EF-TU-GDP release from the unit.
Fourth GTP is used by elongation factor EF-G (translocase) which uses for translocating ribosome by one codon ahead.
Hence in all above four energy units energy is spent to create covalent bond between monomer and its carrier tRNA. Hence correct option is bond between monomer and carrier.
2. The hydropathy index (indicator of hydrophilicity or hydrophobicity) of glutamic acid side chain is -3.5 while for valine is +4.2. Minus sign indicates hydrophilic whereas positive sign indicates hydrophobic. Hence based on this, valine is more hydrophobic.