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In the early 1990s, 7,983 elderly Dutch men and women were included in a prospec

ID: 2936035 • Letter: I

Question

In the early 1990s, 7,983 elderly Dutch men and women were included in a prospective cohort study (follow-up is involved). A number of participants were lost to follow-up during the course of the study.  The investigators computed how many person-years each participant had contributed to the study until January 2000. The total was 52,137 person-years. During follow-up, 2,294 of the participants died, and of these, 577 were due to coronary heart disease.

What is the coronary heart disease-specific mortality rate/density?

8.1  per 1,000 person-years

11.1  per 1,000

25%

60 per 1000 person-years

11.1  per 1,000 person-years

A.

8.1  per 1,000 person-years

B.

11.1  per 1,000

C.

25%

D.

60 per 1000 person-years

E.

11.1  per 1,000 person-years

Explanation / Answer

Coronary heart disease specific mortality rate/density = number of deaths due to coronary disease/total person years contributed by the subjects of the study

= 577/52137

= 0.0111

= 11.1 per 1000 person years (option E)