Physicians specializing in the care of the elderly would expect the clearance of

Question

Physicians specializing in the care of the elderly would expect the clearance of penicillin to be different from that in a young patient in what way? a. The renal clearance of most substances is not affected by age in humans. b. It would be impossible to tell without knowing the status of pulmonary ventilation. c. The renal clearance should be faster in an elderly patient than in a young person. d. The renal clearance should be slower because elderly patients have lost many functional nephrons. e. The renal clearance would be faster if blood flow is normal.

Explanation / Answer

Question 20 :

d) The renal clearance should be slower because elderly patients have lost many functional nephrons.

Nephrons are damaged and lost in older patient kidneys as a result GFR (glomerular filtration rate) is affected. Thus filtration and clearance of drugs and other waste are also directly affected.

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