In the experiment above, bile acids in the blood of WT (white bar) and DKO (blac
ID: 3506489 • Letter: I
Question
In the experiment above, bile acids in the blood of WT (white bar) and DKO (black bar) were measured. (Bile acids help the absorption of dietary fat. After absorption through the gut, bile acids are recycled back to the gut in the blood). What can you conclude from this data?
Put all the data together so far. Why might the DKO mice have had shorter lifespans?
Transport kinetics determines the rate of transport. We talked about three conditions that change kinetics. 1, Did the concentration of solute in DKO vs WT mice explain the change in absorption?
DKO mice absorb less bile acids than WT Bile acids conc in portal vein (g/mL)Explanation / Answer
A) DKO mice absorb less bile acid than wild type.
B)the data show that DkO mice could have dead of starvation.
C) Yes although DKO mice had the same nutrients as WT type.Na was lower that WT and na is a solute for symporter.