Neurotransmitters may be broken down by enzymes or removed from the synapse by r

Question

Neurotransmitters may be broken down by enzymes or removed from the synapse by reuptake to terminate the signal. The most important way that the signal is terminated for ______________ is _______________. A) acetylcholine, reuptake B) norepinephrine, it is broken down by enzymes C) acetylcholine, it is broken down by an enzyme

Nicotinic receptors are located __________ and ___________. A) at (or on cell membranes of cells located in) autonomic ganglia, autonomic effector cell membranes B) on skeletal muscle cell membranes, and autonomic effector cell membranes C) at (or on cell membranes of cells located in) autonomic ganglia, on skeletal muscle cell membrane

Which of the following release(s) acetylcholine as a transmitter? A) sympathetic preganglionic and parasympathetic preganglionic neurons B) parasympathetic postganglionic neurons C) somatic motor neurons D) A and B E) A, B, and C

Explanation / Answer

1)C

Acetylcholine, has a enzyme for inactivation in the synaptic cleft called acetylcholinesterase (AChE). AChE is an enzyme present at all cholinergic synapses which serves to inactivate acetylcholine by hydrolysis. Acetylcholine (ACh), is composed of acetate and choline. AChE breaks ACh into its component parts; acetate and choline. After hydrolysis, acetate quickly diffuses into the surrounding medium, while choline gets taken back into the presynaptic cell by a high affinity choline uptake (HACU) system. Choline is then recycled by the pre-synaptic cell for use in the synthesis of more ACh.

2)Nicotinic receptors are receptor proteins that respond to the neurotransmitter acetylcholine.

C) at (or on cell membranes of cells located in) autonomic ganglia, on skeletal muscle cell membrane

3)E

3)

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