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Please help me to answer the pre-lab qouestions for the following lab: How Sweet

ID: 488178 • Letter: P

Question

Please help me to answer the pre-lab qouestions for the following lab:

How Sweet it is! Sensory Quality and Ester Synthesis

Reading: Why Fries Taste so Good: http://www.pbs.org/pov/foodinc/fastfoodnation_03.php

Nature contains a large number of compounds that smell sweet. Flowers and fruits, in particular, contain compounds whose aromas are pleasing. Chemists have separated, identified, and synthesized many of these compounds, making them available at a reasonable cost for use in cosmetics, household products, cleaners, and even foods. One common compound, ethyl acetate, is often used to remove nail polish.

These compounds are produced or synthesized by specific chemical reactions. One class of compounds that is usually sweet smelling is the esters.   In fact, the main ingredient in artificial flavorings is an ester. Esters contain the functional group

where R1 and R2 are alkyl groups (groups that contain only carbon and hydrogen). The ester octyl acetate, which has the odor of orange peels, has an R1 = CH3 (methyl) and R2 = CH3(CH2)7 (octyl).

                                                                    

                                                                                     Octyl acetate

One method of producing esters is to react a carboxylic acid with an alcohol in an acidic medium. The acid acts as a catalyst. Below, the carboxylic acid acetic acid is treated with the alcohol ethanol to produce the ester ethyl acetate. The acid catalyst is shown as a "H+" over the arrow. Water is produced as a side product.

               Acetic Acid                                       Ethanol                                                       Ethyl Acetate

The name of esters is usually listed in two parts: The group attached to the oxygen is listed first (that group originated from the alcohol, in this case ethanol) with the “ol” ending switched to an “yl” ending. The second name originates from the acid name. Most acids have either an “ic” or an “oic” suffix; in the ester name, that suffix is replaced with either an “ate” or an “oate” suffix. Thus, the new ester above is named as ethyl acetate.

Through this lab we will explore the connection between functional groups and our senses as well as explore the synthesis of several esters.   

Pre-lab

A.Basic Tastes: Complete the table below with appropriate entries for taste and smell sensations

Taste Sensation

Smell Sensation

Chemical substance present

Typical foods

Hydroxyl groups (OH)

Candy

Ions of salt

Pickled vegetables

Hydrogen ions (H+) in acids

Lemons

Amino Acids

Eggs, seafood, MSG*

Bitter

Alkaloids

Caffeine* and pure cocoa

*ingredient in foods and/or beverage

B.Read “Why do Fries Taste so good?” What did you find new in this article? What was most interesting to you?

C.In the article, Eric Schlosser states “Scientists now believe that human beings acquired the sense of taste as a way to avoid being poisoned.” How does that statement relate to the activity in Part A? Do you agree with the statement? Explain.

D.What role do you think the sense of smell plays? On an evolutionary standpoint, why do you think the sense of smell was developed?

E.Why is the flavor industry such an important aspect of foods?

Lab Procedure

A. Senses

B. Ester Synthesis

Today in lab you will be synthesizing seven different esters that are used in the food industry as well as identifying their odors and naming the esters. Combinations for esters are noted in the table below. You and a partner will work together to prepare seven new compounds.

Alcohol

Carboxylic Acid

                                  Ester name

                     Scent

Ester 1

1-pentanol

(n-amyl alcohol)

Acetic acid

Ester 2

Ethanol (ethyl alcohol)

Formic acid

Ester 3

Methanol

(methyl alcohol)

Salicylic acid

Ester 4

Ethanol (ethyl alcohol)

Butyric acid

Ester 5

Butanol (butyl alcohol)

Acetic acid

Ester 6

1-pentanol

(N-amyl alcohol)

Butyric acid

Ester 7

Methanol

(methyl alcohol)

Butyric acid

CAUTION: concentrated sulfuric acid is highly corrosive and should remain in the hood. Glacial acetic acid and formic acid are also corrosive and should be added to testtubes in the hoods. Pentanol, ethanol, methanol, and butanol, and glacial acetic acid are flammable – NO OPEN FLAMES IN THE LABORATORY. Methanol is toxic and should be handled with gloves. Great care should be used when handling all these reagents. Goggles and gloves should be worn at all times.

Procedure

1.Fill a 250 or 500 mL beaker ~ ½ full water. Place beaker on hotplate and heat to 50-60 C while preparing the test tubes (as in #2-4).

2. Label 7 test tubes 1-7 using a Sharpie.

3.For each ester, add 1 mL alcohol and 1 mL carboxylic acid (or 1 scoop for salicylic acid) to the corresponding test tube.

4.Carefully add 3-4 drops of sulfuric acid to each test tube.

5.Carefully place test tubes in hot water bath (50-60 C) for 5-10 minutes.

6.Try to identify the odor of the ester. If the smell of sulfuric acid is too strong (how would that smell?), neutralize the acid with a few drops of 5% sodium bicarbonate.

7.Name the esters you synthesized.

8.Dispose of esters in the container marked “non-halogenated organic waste.”

Explanation / Answer

Esters contain the functional group,

R1-CO-O-R2

Prelab : A. Basic Tastes

Taste                                       Smell             Chemical present

bitter                                     unpleseant           hydroxyl (OH-)

salty                                    depend of salt         Ions of salt

bitter                                      unpleseant           hydronium (H+)

sour/sweet/bitter                     pungent             amino acids

bitter                                         irritant              alkaloid

B. Ester synthesis

                     alcohol              carboxylic acid            Ester Name                                 Scent

Ester 1        1-pentanol             acetic acid              pentyl acetate                               sweet

Ester 2          ethanol                formic acid              ethyl formate                                 rum

Ester 3         methanol             salicylic acid      salicylic acid methyl ester                  minty

Ester 4          ethanol               butyric acid              ethyl butyrate                               fruity

Ester 5          butanol               acetic acid                butyl acetate                              sweet

Ester 6       1-pentanol             butyric acid           pentyl butyrate                               fruity

Ester 7         methanol             butyric acid           methyl butyrate                             sweet