Imagine that you have generated three hybrid (mouse-human) cell lines that conta
ID: 53542 • Letter: I
Question
Imagine that you have generated three hybrid (mouse-human) cell lines that contain the following human chromosomes and protein products of interest:
Line 15:Chromosomes 1,5,6,7,8;Human Proteins X and Z
Line 27:Chromosomes 3,4,7,8;Human Proteins W and Z
Line 34:Chromosomes 2,4,6,8;Human Proteins W, X, and Z
What are the likely chromosome locations of the W, X, Y, and Z genes?
The chromosome location of one of these genes remains unresolved. List that gene as uncertain.
W: _________________; X: _________________; Y: _________________; Z: _________________
Explanation / Answer
As per the information given to us
Line 15:Chromosomes 1,5,6,7,8;Human Proteins X and Z
Line 27:Chromosomes 3,4,7,8;Human Proteins W and Z
Line 34:Chromosomes 2,4,6,8;Human Proteins W, X, and Z
From this information we can see that human protein of interest Z is expressed with chromosome 8. So the likely location of gene Z: chromosome 8. Gene Y: uncertain. Gene X: chromosome 6. Gene W: chromosome 4.