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Part A In a nucleophilic acyl substitution reaction, will an acetate group (Y) o

ID: 580673 • Letter: P

Question

Part A In a nucleophilic acyl substitution reaction, will an acetate group (Y) or a methoxy group (Z) leave from the tetrahedral intermediate? Will a chloro group (Y) or a hydroxyl group (Z) leave from the tetrahedral intermediate formed in a nucleophilic acyl substitution reaction? the bond reforms and a group is eliminated R a tetrahedral intermediate the nucleophile adds to the carbonyl carbon Hints O Z leaves, Z leaves O Y leaves, Z leaves O Z O Y leaves; Y leaves leaves, Y leaves Submit My Answers Give Up

Explanation / Answer

Ans : Y leaves, Y leaves ( Chloro Y is a good leaving group and hydroxy Z is a bad leaving group. Therefore on attack of hydroxide ion on acyl chloride, chloride ion leaves).