Part A How would you design a genetic screen to find genes involved in meiosis?
ID: 62690 • Letter: P
Question
Part A How would you design a genetic screen to find genes involved in meiosis? Genes involved in meiosis can be found by screening E.coIi mutants that are unable to conjugate in inductional conditions. Genes involved in meiosis can be found by screening mutant Arabidopsis stem cells from which sterile plants develop on cloning medium. Genes involved in meiosis can be found by screening mutant Drosophila germ cells from which sterile flies develop after fertilization. Genes involved in meiosis can be found by screening diploid yeast mutants that are unable to produce viable ascospores on sporulation medium.Explanation / Answer
Genes involved in meiosis can be genetically screened by studying meiotic mutants affecting various important stages in meiosis have been identified using a combination of screening methods in which organisms or plants with reduced fertility or completely sterile are involved. The temporal/spatial segregation of meiotic genes can be known by examination of pre-meiotic nuclei and meiotic nuclei in meiotic prophase in a bisexual organism. Thus, genes involved in meiosis can be found by screening mutant Arabidopsis stem cells from which sterile plants develop on cloning medium. Option 2 is correct.