Please answer and explain the following question: Your friend has just joined a

Question

Please answer and explain the following question:

Your friend has just joined a lab that studies vesicle budding from the Golgi and has been given a cell line that does not form mature vesicles. He wants to start designing some experiments but wasn't listening carefully when he was told about the molecular defect of this cell line. He's too embarrassed to ask and comes to you for help. He does recall that this cell line forms coated pits but vesicle budding and the removal of coat proteins don't happen. Which of the following proteins might be lacking in this cell line Clathrin Rab dynamin adaptin

Explanation / Answer

Dynamin is a large GTPase involved in budding and scission of nascent vesicles from parent membrane leading to formation of mature vesicles.

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