In the Fischer synthesis, it is used for synthesizing monosaccharides. It procee
ID: 699375 • Letter: I
Question
In the Fischer synthesis, it is used for synthesizing monosaccharides. It proceeds through synthesis and hydrolysis of a cyanohydrins, thereby elongating the carbon chain of an aldose by one unit. Hence, the intermediate of Fischer synthesis is option (b).
Ruff degradation is a synthetic process to remove one carbon atom from an aldose molecule. It proceeds via oxidation of aldehyde moiety of an aldose molecule to carboxylic acid. The resulting compound will lose one CO2 molecule forming an aldose molecule which has one carbon less to the parent aldose. Hence the intermediate is the acid; option (e).
Explanation / Answer
11. of the structures given, which is the second intermediate of the Fischer synthesis and third intermediate of the Ruff degradation? You can start of finish your synthesis with an open or closed form. C.