Imagine a cellular protein composed of 3000 amino acid residues in one continuou
ID: 89903 • Letter: I
Question
Imagine a cellular protein composed of 3000 amino acid residues in one continuous polypeptide chain. This protein is almost certainly... extracellular globular multidomain composed of mostly alpha-helical regions The eukaryotic chromosomes are organized inside the nucleus with a huge compaction ratio of several thousand-fold. What is responsible for such tight packaging of DNA? The various histone/chromatin proteins that wrap and fold the DNA The nuclear envelope which encapsulates the chromosomes The nuclear matrix that provides a firm scaffold All of the above On the ribosome, the mRNA is read from ___________and the polypeptide chain is synthesized from _____ 5 to 3 C- to N-terminus 5' to 3:N- to C-terminus 3 to 5:C- to N-terminus D. 3 to 5:N-to C-terminus Which of the following DNA repair pathways can accurately repair a double-strand break? Base excision repair (BER) Nucleotide excision repair (NER) Non-homologous end joining (NHE) Homologous recombination (HR) Cyclin B1, a key cell cycle regulatory protein in vertebrates, is mostly cytosolic before mitosis. Early in mitosis, however, the protein is phosphorylated by certain protein kinases and consequently accumulates in the nucleus. How can phosphorylation bring about nuclear accumulation of this protein? Phosphorylation within the nuclear localization signal inhibits signal function Phosphorylation within the nuclear export signal enhances signal function Phosphorylation within the nuclear export signal interferes with signal function Phosphorylation elsewhere on the protein enhances binding to cytosolic proteinsExplanation / Answer
Answers:
1) Imagine a cellular protein composed of 3000 amino acid residues in one continuous peptide chain. This protein is almost certainly.
2) The eukaryotic chromosomes are organized inside the nucleus with a huge compaction ratio of several-thousand fold. What is responsible for such tight packaging of DNA?
3) On the ribosome, the mRNA is read from 5’ to 3’ and the polypeptide chain is synthesized from N – to – C terminus
4) Which of the following DNA repair pathways can accurately repair a double-strand break?
5) Cyclin B1, a key cell cycle regulator protein in vertebrates, is mostly cytosolic before mitosis. Early in mitosis, however, the protein is phosphorylated by certain protein kinases and consequently accumulates in the nucleus. How can phosphorylation bring about nuclear accumulation of this protein?