Hexokinase IV has a Km value that is substantially higher than the Km for other
ID: 917381 • Letter: H
Question
Hexokinase IV has a Km value that is substantially higher than the Km for other hexokinases. What is the significance of this fact?
The higher Km reflects lower affinity for its substrate, and therefore this kinase is only operational when glucose levels are low.
The higher Km reflects higher affinity for its substrate, and therefore this kinase is only operational when glucose levels are low.
The higher Km reflects lower affinity for its substrate, and therefore this kinase is only operational when glucose levels are high.
The higher Km reflects high affinity for its substrate, and therefore this kinase is only operational when glucose levels are high.
Explanation / Answer
option 3 The higher Km reflects lower affinity for its substrate, and therefore this kinase is only operational when glucose levels are high.
hexokinase IV involves enzymes like glucokinase which operates in the above condition.