Place the steps of extravasation of neutrophils to infected tissue sites in the

Question

Place the steps of extravasation of neutrophils to infected tissue sites in the correct chronological order. (1 = earliest event, 7 = latest event) Binding of neutrophil sialyl-Lewis^x (s-LE^x) carbohydrates to selectins Rolling of neutrophils is arrested Expression of selectins on surface of helium by cytokines IL-1beta and TNF-alpha Binding of CXCL8 to CXCLR1 on neutrophils Diapedesis of neutrophils between endothelial cells Neutrophil integrins LFA-1 increase their affinity for endothelial adhesion molecules ICAM-1 Migration of neutrophils to sites of infection following CXCL8 chemokine gradient

Explanation / Answer

The steps of extravasation of neutrophils ro infected tissue sites in the correct chronological order (from first step to last step) are as follows

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