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Study the nucleotide sequences of wild type and its mutant gene below. Wild type

ID: 93033 • Letter: S

Question

Study the nucleotide sequences of wild type and its mutant gene below. Wild type: GAACCATG Mutant: GAACAATG This mutation can best be called: a) Pont b) Substitution c) Transversion. d) All of the above Study the nucleotide sequences of wild type and its mutant gene below. Mutant GAACATG Wild t GAACCATG The mutation can best be called: a) Addition b) Deletion c) Both Study the nucleotide sequences of wild type and its mutant gene below. Wild type: Protein: Met-Pro-Glu-Pro-Lys-Met DNA: ATG CCC GAA ATG Mutant: Protein: Met-Pro-stop Protein: ATG CCC TAA CCC AAA ATG This mutant can best be called: a) Non-sense b) Silent c) Frameshift d) Mis-sense e) All of the above

Explanation / Answer

A mutation in DNA alters the mRNA code, which in turn can change what kind of protein is produced. we can say there are 3 types of mutation !)A missense mutation makes a slight change to a protein

2)a nonsense mutation blocks a protein's production, Nonsense mutations always result in the early termination of a polypeptide. In other words, the chain stops short, and the protein is never completed

3)a silent mutation does not affect the protein at all.

These They all result from the switching of one base for another.

Frameshift:-

Insertions occur when one or more base pairs are added to the sequence, and deletions occur when base pairs are removed from the DNA sequence. the length of the DNA changed because of the add or subtract one base pair from the code. which can have drastic effects on the DNA code and the final protein.

Q 29) as we can se there is no change in Wild Type DNA and Mutation DNA so it is Silent mutation.

Q30) as we can se CCC is changed to CCT there is a slit change in the DNA of the given protein so this is callend mis- sense mutation( a point mutation that changes a codon to indicate a different amino acid)

Q 31)as we can see G is added (inserted) GAA convertef into GGA so the whole DNA is changed so as RNA so this will effect our Amino Acid . so this is frameshift (insertion ) mutation.