QUESTION 2 Concerning retinoblastoma, which of the following is not predicted by
ID: 93730 • Letter: Q
Question
QUESTION 2
Concerning retinoblastoma, which of the following is not predicted by the two-hit model?
sporadic tumors will be unifocal (i.e., one eye affected)
inherited tumors will be multifocal
two copies of the gene must be disabled for tumor expression to occur
imprinting of human chromosome 15 will be observed
sporadic tumors will be unifocal (i.e., one eye affected)
inherited tumors will be multifocal
two copies of the gene must be disabled for tumor expression to occur
imprinting of human chromosome 15 will be observed
Explanation / Answer
I think imprinting of human chromosomes 15 observation was not get predicted in two hit model which concerning to retinoblastoma because retinoblastomia will predict the multifocal tumors and genes of two copies and also sporadic tumors where one eye get effected.So i think last option is correct