Consider the endocrine feedback systems shown in Figure 1. Please indicate the s
ID: 98491 • Letter: C
Question
Consider the endocrine feedback systems shown in Figure 1. Please indicate the short-term (minutes to hours) and long-term (days) effects on the plasma level of Hormone and on the output of the Target Tissue of the following changes listed below. Explain your reasoning.
a. Increase in X
b. Increase in the Concentration of Carrier Protein
c. Liver or Kidney disorder
d. Inactive receptor at the Target Tissue
e. Inactive receptor at the Endocrine Gland
f. Insensitivity of the Endocrine Gland to X
Figure 1 Carrier/rotein Stimulus EndocrinExplanation / Answer
increase (ST)
comes back to normal levels as amount of X subsidizes (LT)
increase (ST)
comes back to normal levels as amount f X subsidizes resulting in low H (LT)
PLASMA LEVELS TARGET TISSUE aincrease (ST)
comes back to normal levels as amount of X subsidizes (LT)
increase (ST)
comes back to normal levels as amount f X subsidizes resulting in low H (LT)
b increased (ST and LT) output increases initially(ST) but will obtain a constant value as saturation of the receptor is reached (LT) c normal (ST and LT) normal (ST and LT) d normal (ST and LT) no output (ST and LT) e no H in plasma (ST and LT) no output (ST and LT) f no H in plasma (ST and LT) no output (ST and LT)