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In genetic complementation testing, crosses are performed between pure-breeding

ID: 25285 • Letter: I

Question

In genetic complementation testing, crosses are performed between pure-breeding strains for recessive mutations that confer the same mutant phenotype. If the two mutations are in different genes, then what phenotypic ratios would be expected among the progeny?

A) All of the F1 progeny would display the mutant phenotype associated with the parents.
B) All of the F1 progeny would be wild-type.
C)There will be a 1:1 ratio of mutant to wild-type.
D)All of the F1 progeny would display a novel mutant phenotype that differs from that of the parents.

Explanation / Answer

If the two mutations are in different genes, then All of the F1 progeny would be wild-type.