Please answer and explain. Thanks! Ligand Gated Ion Leak Channel # 800 100 [ECF
ID: 3475689 • Letter: P
Question
Please answer and explain. Thanks! Ligand Gated Ion Leak Channel # 800 100 [ECF ICF mM Ion mM 6 143 Channel # 590 480 K+ 138 Na+ What would the resting membrane potential be for this cell? . To what would the membrane potential change if a drug was introduced that blocked the K+ leak channels? . To what would the membrane potential change from rest if a stimulus opened the Nat ligand gated ion channels? Which direction would Na* move across the membrane if the membrane potential was 80 mV? Which direction would K move across the membrane if the membrane potential was -80 mV?Explanation / Answer
By the use of Goldman-Hodgkin-Katz Equation please find below answer:
1.Resting membrane potential for this cell is -0.16139121926721367 V
2.Membrane potential change would be -216.15 mV if a drug was introduced that blocked the K+ leak channels.
3.Membrane potential change would be 190.65mV if a drug was introduced that blocked the Na+ ligand gated ion channels
4.The driving force acting on K+ leads to K+ efflux from the cell,if themembrane potential was 80 mV
5. The driving force acting on Na+ leads to Na+ influx into the cell,if themembrane potential was -80 mV
Thanks